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5. RECOMENDATIONS

5.1 In the interests of public health and agriculture and in view of the needs of the Codex Committee on Pesticide Residues, the Meeting recommended that Joint Meetings on Pesticide Residues should continue to be held annually.

5.2 The Meeting recommended (Section 2.3) that

(1) Maximum Residue Limits for Monitoring (MRLMs) be applied to new or periodic review chemicals reviewed by future FAO Panels of the JMPR, and that they be clearly indicated as such.

(2) the information needed for the JMPR to refine its estimates of dietary intakes continue to be clearly stated in JMPR reports and evaluations.

5.3 In connection with the estimation of residues in animal commodities found in feeding studies the Meeting recommended (Section 2.4) that

(1) reports of future feeding studies should record the feeding levels primarily on a dry weight basis.

(2) worked examples of the derivation of maximum residue and STMR levels should be developed in time for the 1998 JMPR.

5.4 The Meeting recommended (Section 2.5) that

(1) the CCPR request national governments to provide information on situations where extrapolation of residue data to minor crops is considered feasible at the national level.

(2) national governments prepare data submissions for commodities of concern when the specific pesticides are scheduled for review by the JMPR.

5.5 The Meeting recommended (Sections 2.6 and 4.19) that a full re-evaluation of the toxicological and residue aspects of lindane be undertaken at a future Meeting.

5.6 The Meeting recommended (Sections 3.1 and 4.1) that

(1) Codex MRLs should accommodate the maximum residue levels estimated both by the JMPR and JECFA.

(2) the JMPR and JECFA take note of each other's definitions of residues for enforcement purposes and that these be harmonized to provide definitions suitable for compliance with Codex MRLs.

(3) JECFA be requested to suggest an appropriate maximum residue level in cattle meat, and to consider accepting the broader definition of the residue to accommodate the residues which occur as a result of agricultural as well as veterinary uses.

5.7 In order to ensure that appropriate samples of fat are taken in studies of fat-soluble compounds the Meeting recommended (Section 3.2) that

(1) in livestock transfer (feeding) studies with fat-soluble pesticides samples of sub-cutaneous, abdominal (omental, peritoneal, mesenteric) and renal fat should be taken from an animal and analysed separately.

(2) in external animal treatment studies a sample of the fat at the treatment site, in addition to the three fat types required in the feeding studies specified in recommendation 1, should be taken and analysed separately.

(3) in animal studies residue levels should be expressed on the lipid content of the fat (rendered or extracted fat may be assumed to be 100% lipid). The lipid content of the fat in trimmable fat or fatty tissue should also be reported.

(4) the CCPR ad hoc Working Group on Methods of Analysis and Sampling should include a more precise description of carcase fat in the tables of "Portion of Commodities to which Codex Maximum Residue Limits Apply and which is Analysed."

(5) in recommending an MRL the JMPR should estimate the maximum residue level which might occur in any fat depot in the animal, recognizing the possibility that a regulatory authority may take a sample of any type of fat.

(6) the recommendations for changed JMPR practices would initially apply only to evaluations of data on new and periodic review compounds.

(7) the content and recommendations of Section 3.2 of the report should be referred to JECFA for information and comment, with the intention of harmonising requirements and procedures relating to the nature of fat samples in studies with fat-soluble compounds.

5.8 The Meeting recommended (Section 3.3) that

(1) the chronic dietary risk posed by the two groups of dithiocarbamate pesticides be assessed using STMR levels and other factors, as described in Guidelines for predicting dietary intake of pesticide residues (WHO, 1997). For those commodities potentially containing more than one dithiocarbamate pesticide for which residue data have been accepted by the JMPR, the risk assessment should be based on the pesticide that contributes most to the estimated intake in relation to its ADI.

(2) an ADI adjustment approach should be used and that an example of this approach should be developed in 1998.

5.9 The Meeting recommended (Section 4.17) that

(1) glyphosate be re-evaluated by the JMPR, as new data have become available since the last JMPR evaluation for toxicity in 1986, and

(2) the significance of the appreciable levels of AMPA which occur in soya beans should be evaluated in a future periodic review, even though they are not believed to pose any risk to consumers.


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