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APPENDIX III: PROPOSED DRAFT MAXIMUM RESIDUE LIMITS FOR VETERINARY DRUGS ADVANCED TO STEP 5/8

Benzylpenicillin/Procaine benzylpenicillin

ADI:

30 µg-penicillin/person/day (1998) Residues of benzylpenicillin and procaine benzylpenicillin should be kept below this level.

Residue Definition:

Benzylpenicillin


Species

Tissue

MRL

(µg/kg)


Step

JECFA

CCRVDF

cattle

muscle

50



5/8

50


pig

muscle

50



5/8

50


chicken

muscle

50


1/

5/8

50


cattle

liver

50



5/8

50


pig

liver

50



5/8

50


chicken

liver

50


1/

5/8

50


cattle

kidney

50



5/8

50


pig

kidney

50



5/8

50


chicken

kidney

50


1/

5/8

50


cattle

milk

4

(µg/l)


5/8

50


1/ Applies to procaine benzylpenicillin only.
Febantel/Fenbendazole/Oxfendazole

ADI:

0-7 µg/kg body weight (1998) Group ADI

Residue Definition:

Sum of fenbendazole, oxfendazole and oxfendazole sulphone, expressed as oxfendazazole sulphone equivalents


Species

Tissue

MRL

(µg/kg)

Step

JECFA

CCRVDF

goat

muscle

100


5/8

50


horse

muscle

100


5/8

50


goat

liver

500


5/8

50


horse

liver

500


5/8

50


goat

kidney

100


5/8

50


horse

kidney

100


5/8

50


goat

fat

100


5/8

50


horse

fat

100


5/8

50



Keys for List of MRLs for Veterinary Drugs

ADI

Acceptable Daily Intake (expressed in micrograms/kilogram body weight)

Tissue

Muscle, Liver, Kidney, Fat, Fat/Skin, Milk or Egg

MRL

Maximum Residue Limit (unless noted otherwise, expressed in micrograms/kilogram)

Step

Step of the MRL at the time of consideration by the CCRVDF or Year of its adoption by the Codex Alimentarius Commission

JECFA

Meeting number of the Joint FAO/WHO Expert Committee on Food Additives where the substance was evaluated and/or MRL recommended/considered

CCRVDF

Session number of the CCRVDF where the MRL was considered and Appendix number of its report where the MRL is contained.


Fluazuron

ADI:

0-40 µg/kg body weight (1997)

Residue Definition:

Fluazuron


Species

Tissue

MRL

(µg/kg)

Step

JECFA

CCRVDF

cattle

muscle

200


5/8

48


cattle

liver

500


5/8

48


cattle

kidney

500


5/8

48


cattle

fat

7000


5/8

48



Moxidectin

ADI:

0-2 µg/kg body weight (1995)

Residue Definition:

Moxidectin


Species

Tissue

MRL

(µg/kg)


Step

JECFA

CCRVDF

deer

muscle

20


1/

5/8

45, 47, 48, 50


deer

liver

100


1/

5/8

45, 47, 48, 50


deer

kidney

50


1/

5/8

45, 47, 48, 50


deer

fat

500


1/

5/8

45, 47, 48, 50


1/ Revised MRL.
Nicarbazin

ADI:

0-400 µg/kg body weight (1998)

Residue Definition:

N, N'-bis(4-nitropheyl)urea


Species

Tissue

MRL

(µg/kg)


Step

JECFA

CCRVDF

chicken

muscle

200


1/

5/8

50


chicken

liver

200


1/

5/8

50


chicken

kidney

200


1/

5/8

50


chicken

fat/skin

200


1/

5/8

50


1/ Broilers.
Spectinomycin

ADI:

0-40 µg/kg body weight (1994)

Residue Definition:

Spectinomycin


Species

Tissue

MRL

(µg/kg)

Step

JECFA

CCRVDF

sheep

muscle

500


5/8

50


sheep

liver

2000


5/8

50


sheep

kidney

5000


5/8

50


sheep

fat

2000


5/8

50


chicken

eggs

2000


5/8

50



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