On 10-12 April 2019, the Organisation for Economic Co-operation and Development (OECD) hosted a conference on "Regulation of externally applied dsRNA-based products for the management of pests" at OECD Headquarters in Paris, France. Its main objectives were to provide participants with a summary of the state of the art of double-stranded RNA (dsRNA)-based product use in agriculture; exchange information on the current status and future possibilities for the regulation of externally applied dsRNA-based products that are proposed for use as pesticides; facilitate discussions on the impact of the use of dsRNA pesticides on the environment and health and implications for current regulations; and inform regulatory policy and facilitate harmonised approaches across governments. A short overview of the conference, linking to related information and documents, is provided in the latest issue (June 2020) of the OECD Biotechnology Update, prepared by the OECD Internal Co-ordination Group for Biotechnology. The 31-page newsletter provides updated information on activities, publications and events at the OECD. See http://www.oecd.org/env/ehs/biotrack/oecdbiotechnologynewsletterupdates.htm or contact [email protected] for more information.