The COVID-19 crisis has created a moment where existing calls for agroecology acquire new relevance. Agroecology provides a path to reconstruct a post-COVID-19 agriculture, one that is able to avoid widespread disruptions of food supplies in the future by territorializing food production and consumption. There are five main areas in which agroecology can point the way to a new post-COVID-19 agriculture: overcoming the pesticide treadmill, enriching nature’s matrix, revitalizing small farms, creating alternative animal production systems and enhancing urban agriculture.