The call on Sustainable Food Security dedicates €431 million to ensure sufficient, safe and nutritious food for all, while safeguarding natural resources. Tackling the challenge of how to feed 9 billion people sustainably by 2050, this call puts approaches that aim at using nature and resources better at the heart of research investments. It strongly focuses on climate-smart and environment-smart production systems. It also aims to improve the nutritional added value and the safety of food. Considering the global character of the challenge, it invests in international cooperation with €52 million dedicated to cooperation between Europe and China and Africa.