To secure technical support in developing small animal sub sector in West Nile region, in 2012, the Agency For Accelerated Regional Development (AFARD) signed a Memorandum of Understanding with Africa Institute for Strategic Animal Resource Services and Development (AFRISA) a not-For-Profit and autonomous government institution furthering Academic-Community-Private-Public Partnership (ACP3) engagement platform for the College of Veterinary Medicine, Animal Resources and Bio-security (COVAB), Makerere University. Since then, AFARD and AFRISA have undertaken various successful partnerships to propel local poultry production by equipping national and refugee smallholder farmers with basic knowledge and skills in poultry husbandry and especially the new programmed hatching technology. It is in this spirit that this manual was written by Dr. Eneku Wilfred of AFRISA. Local chicken production has been identified as one of the livestock enterprises with great potential for reducing poverty, malnutrition and gender inequality among rural communities of West Nile regions of Uganda. Although the main aim of rearing the chicken is not for income generation, with the increasing demand for local chicken there is an enormous opportunity that can be tapped to both improve household nutritional needs as well as increased income. This is possible when the key hinderances to increased production and productivity such as diseases, predators, poor husbandry practices, and lack of appropriate skills are addressed. Programmed hatching technology provides a faster means by which smallholder farmers can increase the number of their poultry production cycle in a year while ensuring reduction in mortality of chicks.