Online Edition: "Residues of some veterinary drugs in foods and animals"

Online help Terminology

This database contains the most recent information on maximum residue levels for veterinary drugs as recommended by JECFA. All monographs published in the FAO Food and Nutrition Papers 41 can be accessed in an electronic format. These monographs are available only in English although some parts of the database, the query page as well as the background information are provided in English, French, Spanish, Arabic and Chinese.

Veterinary Drug

Dexamethasone

Functional class

Glucocorticosteroid

Latest evaluation

2008

JECFA meeting

ADI

0-0.015 µg/kg b

ADI status

Full

Residue monographs

6-2009-dexamethasone.pdf

41-7-dexamathazone.pdf

41-11-dexamethasone.pdf

41-6-dexamethasone.pdf

Marker residue

Dexamethasone

Maximum residue limits
(MRL) recommended

Cattle	Kidney	1 µg/kg	F
Cattle	Liver	2 µg/kg	F
Cattle	Milk	0.3 µg/l	F
Cattle	Muscle	1 µg/kg	F
Horse	Kidney	1 µg/kg	F
Horse	Liver	2 µg/kg	F
Horse	Muscle	1 µg/kg	F
Pig	Kidney	1 µg/kg	F
Pig	Liver	2 µg/kg	F
Pig	Muscle	1 µg/kg	F

Other remarks

Summary of the evaluation

The appropriate target tissues are liver or kidney and milk. A suitable validated routine method was available for monitoring dexamethasone in bovine milk and liver at 0.3 µg/l and 2.0 µg/kg, respectively. A suitable validated routine method was available for monitoring dexamethasone in bovine muscle and kidney at 1.0 µg/kg, but not at 0.5 µg/kg. No validated method for horses and pigs was provided or could be found, but the method provided for cattle tissue is adequate to be extended to pig and horse tissues. The recommended MRLs were based on the performances of the analytical methods at twice the LOQ.