Food safety and quality
|
|
|
Online help Terminology
This database contains the most recent information on maximum residue levels for veterinary drugs as recommended by JECFA. All monographs published in the FAO Food and Nutrition Papers 41 can be accessed in an electronic format. These monographs are available only in English although some parts of the database, the query page as well as the background information are provided in English, French, Spanish, Arabic and Chinese.
Veterinary Drug |
Estradiol-17beta |
Functional class |
Production aid |
Latest evaluation |
1999 |
JECFA meeting |
52 |
ADI |
0-0.05 µg/kg bw |
ADI status |
Full |
Residue monographs |
|
Marker residue |
|
Maximum residue limits (MRL) recommended |
Cattle | Fat | Not Specified | F | Cattle | Kidney | Not Specified | F | Cattle | Liver | Not Specified | F | Cattle | Muscle | Not Specified | F |
|
Other remarks |
|
Summary of the evaluation |
The Committee noted that, although the hormone concentrations found in specific populations of treated animals were often statistically significantly higher than the corresponding values for concurrent controls, they were within the physiological range of concentrationsof these substances in cattle and that the calculated excess intakes contributed only a small additional amount of hormone to the intakes resulting from consumption of other foods of both animal and plant origin. On the basis of the available data, the Committee concluded that there would be no need to specify numerical MRLs for estradiol-17beta, progesterone and testosterone and recommended MRLs "not specified" for the edible tissues of cattle when the products are used according to Good Practice in the Use of Veterinary Drugs. The Committee recommended, however, that the total intake of estrogenic residues resulting from the use of any approved hormonal product be kept below the calculated excess intake levels. TRS 893 |
|
|
|