العربية
中文
français
Español
Food safety and quality
| share
 

Online Edition: "Residues of some veterinary drugs in foods and animals"

Online help   Terminology

This database contains the most recent information on maximum residue levels for veterinary drugs as recommended by JECFA. All monographs published in the FAO Food and Nutrition Papers 41 can be accessed in an electronic format. These monographs are available only in English although some parts of the database, the query page as well as the background information are provided in English, French, Spanish, Arabic and Chinese.

Veterinary Drug Lincomycin
Functional class Antimicrobial agent
Latest evaluation 2004
JECFA meeting 62
ADI 0-30 µg/kg bw
ADI status Full
Residue monographs  
41-16-lincomycin.pdf
41-13-lincomycin.pdf
41-14-lincomycin.pdf
Marker residue Parent drug
Maximum residue limits
(MRL) recommended
CattleMilk150 µg/kgF
ChickenFat100 µg/kgF
ChickenKidney500 µg/kgF
ChickenLiver500 µg/kgF
ChickenMuscle200 µg/kgF
PigFat100 µg/kgF
PigKidney1500 µg/kgF
PigLiver500 µg/kgF
PigMuscle200 µg/kgF
Other remarks A separate MRL of 300 mg/kg for skin with adhering fat in pigs was recommended in order to reflect the high concentrations found in the skin of pigs. For consistency, an MRL of 300 mg/kg for skin with adhering fat in chickens was also recommended.
Summary of the evaluation In reviewing the MRLs recommended at its fifty-fourth meeting, the Committee at its present meeting took into account the following factors:
- The ADI of 0-30 mg/kg bw allocated by the Committee at its fifty-fourth meeting was based on a microbiological end-point. This ADI is equivalent to an acceptable maximum daily intake of 1800 µg of antimicrobially active residues of lincomycin for a 60 kg person.
- Parent lincomycin is the only residue with significant antimicrobial activity in tissues of chickens and pigs.
- Kidney and liver contain the highest concentrations of residues in chickens and pigs and pid=63155; however, the new studies confirmed that the concentrations of residues in kidney and liver are similar in chickens, but differ by a factor of three in pigs.
- The new studies suggest that the MRLs for skin/fat of chickens and for muscle of pigs should be higher than those recommended at the fifty-fourth meeting. The MRLs for fat could be maintained for bot hspecies, provided that a separate MRL was recommended for skin with adhering fat in pigs in order to reflect the high concentrations found in the skin of that species.
- For residue control programmes, it would be appropriate to harmonize the MRLs for chicken and pig tissues as far as possible.
- The temporary MRLs for tissues of cattle and sheep should be withdrawn, as the requested information was not provided.
- No data were provided on lincomycin residues in hen's eggs.
Daily consumption of 100 g of liver, 50 g of kidney, 300 g of muscle and 50 g of fat of pigs and 1500 g of cow's milk would result in a theoretical maximum daily intake of 415 µg per person per day or 23% of the ADI for a person with a body weight of 60 kg.
TRS 911