The Rome Chapter focuses mainly on themes such as Food Security, Nutrition and agricultural development. Its aims at safeguarding the interests of the developing countries, advocating for the achievement of the Sustainable Development Goals.

The Rome Chapter operates in collaboration with the three Rome-based agencies, known as RBAs: the Food and Agriculture Organization of the United Nations (FAO), the World Food Programme (WFP) and the International Fund for Agricultural Development (IFAD).

Through effective inter and intra-group lobbying and negotiation, the Rome Chapter ensures that the plight of the poor in developing countries is considered, and features as a priority on the food security agenda.