Diazinon was first evaluated by the 1965 JMPR and has been reviewed several times since. In 1993 a periodic review was conducted and in 1994 a new MRL was recommended for hops. The 1993 JMPR recommended, among other items, an increase in the CXL for pome fruits from 0.5 to 2 mg/kg and the withdrawal of the CXLs for animal commodities in the absence of animal transfer studies and data from uses as an ectoparasiticide.
The CCPR in 1995 and 1996 endorsed most of the recommendations of the 1993 JMPR with the exception of the proposed MRL for pome fruits and the recommended withdrawal of the CXLs for milks and the meat of cattle, pigs and sheep. The CXLs for animal commodities were retained pending review by the 1996 JMPR of data on new animal feeding trials to be submitted by Australia and the manufacturer. The 1993 proposal for pome fruit was held at step 7C by the 1996 CCPR, mainly owing to concern at the potentially high dietary intake from this source.
The Meeting received (1) data on residues and information on GAP for uses of diazinon as an ectoparasiticide, together with animal transfer studies, from the manufacturer (2) summarized data on residues in pome fruit, plums and carrots from Germany (3) monitoring data and information on GAP and national MRLs from Poland (4) information on GAP for mushrooms in the UK and (5) an Australian submission on residues of diazinon in cattle resulting from ectoparasite control. Summary data on residues and information on GAP for the use of diazinon on rice in Thailand were also received. Summary data were not considered to be an adequate basis for estimating maximum residue levels.
Formulations
EC and WP formulations for crop protection were mentioned in the 1993 Evaluations. EC and WP formulations are also available for the treatment of animals for ectoparasites. The most important, and used in the ectoparasite control trials, were a 250 EC with the formulation code A-7182 (250 g ai/l, trade name Neocidol, a 600 EC with the formulation code A-3695 J (600 g ai/l, trade name Neocidol) and to a lesser extent a 60 EC with the formulation code A-139F (60% w/w, trade name Top Clip Gold Shield). The compositions of these formulations were available to the Meeting. When these three were applied as a spray to sheep at the same nominal (recommended) rate of 600 ppm no differences were found in the resulting residues in blood or fat (Morrison, 1994).
Other code numbers used for diazinon include G 24'480, CGA 31'331, OMS 469 and GNT 19507. Other trade names of formulations for animal health uses include Dimpygal, Nucidol, Sarnicida-Garrapaticida, Vetsarol, Clik, Spike, Protector and Kacador, and for other uses Banosan, Antigal, Galton, Gal-Wash, Galesan, Paragal and Eureka.
