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Annex I

ACCEPTABLE DAILY INTAKES, RESIDUE LIMITS AND SUPERVISED TRIALS MEDIAN RESIDUES PROPOSED AT THE 1996 MEETING

The Table of recommendations includes maximum Acceptable Daily Intakes (ADIs) and Maximum Residue Limits (MRLs). It should be noted that MRLs include draft MRLs and Codex MRLs (CXLs). The MRLs recommended by the JMPR on the basis of its estimates of maximum residue levels enter the Codex procedure as draft MRLs. They become Codex MRLs when they have passed through the procedure and have been adopted by the Codex Alimentarius Commission.

In general, the recommended MRLs listed for compounds which have been reviewed previously are additional to, or amend, those recorded in the reports of earlier Meetings. For compounds re-evaluated in the CCPR periodic review programme however, both new and previous recommendations are listed because such re-evaluations are regarded as replacing the original evaluation rather than supplementing it.

Some ADIs may be temporary: this is indicated by the letter T and the year in which re-evaluation is scheduled in parenthesis below the ADI. All recommended MRLs for compounds with temporary ADIs are necessarily temporary, but some recommendations are designated as temporary (TMRLs) until required information has been provided and evaluated, irrespective of the status of the ADI. Such recommendations are followed by the letter T in the table. (See also the list of qualifications and abbreviations below.)

In response to recommendations of a Joint FAO/WHO Consultation on Guidelines for predicting the Dietary Intake of Pesticide Residues held in York, the UK, in 1995, the 1996 Meeting has extended its estimations of residues to include calculations of the median residues found in supervised trials (STMRs) in order to provide a basis for the estimation of the dietary intake of the pesticides reviewed. The estimated STMRs are included in the Table of ADIs and MRLs. Further details of the response of the Meeting to the York Consultation are given in Section 2.2.1 of this report, and information about an informal workshop held in The Hague, The Netherlands, in April 1996 to consider the implementation of its recommendations by the JMPR in Section 2.2.3. The report of this Workshop is reproduced as Annex III.

Attention is drawn to Section 3.1 of the report of the present Meeting: 'Definition of the residues of fat-soluble compounds'. Residues of such compounds are distinguished in the Table of Recommendations by the parenthetic note '(fat-soluble residue)' on a line below the residue definition.

The following qualifications and abbreviations are used.

* following recommended MRL

At or about the limit of determination

* following name of pesticide

New compound

** following name of pesticide

Compound reviewed in CCPR periodic review programme

E

Extraneous Residue Limit (ERL).

F following recommendations for milk

The residue is fat-soluble and MRLs for milk and milk products are derived as explained in the introduction to Part 2 of the Guide to Codex Maximum Limits for Pesticide Residues and to Volume II of the Codex Alimentarius.

(fat) following recommendations for meat

The recommendation applies to the fat of the meat.

Po

The recommendation accommodates post-harvest treatment of the commodity.

PoP following recommendations for processed foods (classes D and E in the Codex Classification)

The recommendation accommodates post-harvest treatment of the primary food commodity.

STMR

Supervised Trial Median Residue (see explanation on previous page).

STMR-P

An STMR for a processed commodity calculated by applying the mean concentration or reduction factor for the process to the STMR calculated for the raw agricultural commodity.

T following ADIs

The ADI is temporary, and due for re-evaluation in the year indicated.

T following MRLs

The MRL is temporary, irrespective of the status of the ADI, until required information has been provided and evaluated.

V following recommendations for commodities of animal origin

The recommendation accommodates veterinary uses.

W in place of an MRL

The previous recommendation is withdrawn.

If a recommended MRL is an amendment, the previous value is also recorded. The absence of a figure in the "Previous" column indicates that the recommendation is the first for the commodity or group concerned.

The Table includes the Codex Classification Numbers (CCNs) of both the compounds and the commodities listed, to facilitate reference to the Guide to Codex Maximum Limits for Pesticide Residues and other Codex documents.

Commodities are listed in alphabetical order. This is a change from earlier practice where commodities were listed in the order of the "Types" in the Codex Classification of Foods and Animal Feeds, and in alphabetical order within each Type. The change was made to facilitate checking and comparison with the CCPR Tables of MRLs, which are in alphabetical order.

ACCEPTABLE DAILY INTAKES (ADIs), MAXIMUM RESIDUE LIMITS (MRLs) AND SUPERVISED TRIALS MEDIAN RESIDUES (STMRs) 1

1 See explanation on pp. xv and 617

Pesticide (Codex ref. No.)

ADI (mg/kg bw)

Commodity

Recommended MRL or ERL (mg/kg)

STMR (mg/kg)

CCN

Name

New

Previous

Acephate

0.03

VB 0400

Broccoli

2

-1

0.11

(095)


VB 0041

Cabbages, Head

2

-1

0.33



VB 0404

Cauliflower

2

-1

0.11



VO 0448

Tomato

1

-1

0.38




Tomato, canned



0.19 P2




Tomato, canned juice



0.35 P




Tomato, bulk paste



1.52 P




Tomato, canned purée



0.68 P




Tomato, wet pomace



0.23 P




Tomato, dry pomace



0.38 P



Residue

(for MRLs & STMRs): acephate



Notes:

1 Previous recommendation withdrawn by 1994 JMPR




2 STMR-P

Aldicarb

0.003

VR 0589

Potato

0.5

0.5 T

0.077

(117)



Potato chips



0.056 P1




Potato fries



0.045 P




Potato, microwaved



0.065 P




Potato, baked



0.050 P



Residue

(for MRLs & STMRs): Sum of aldicarb, its sulfoxide and its sulfone, expressed as aldicarb.



Notes:

1 STMR-P

Bifenthrin

0.02

GC 0654

Wheat

0.5 Po

0.05*

0.255

(178)


CM 0654

Wheat bran, unprocessed

2 PoP

-

0.89 P1



CF 1211

Wheat flour

0.2 PoP

-

0.076 P



CF 1212

Wheat wholemeal

0.5 PoP

-

0.21 P



Residue

(for MRLs & STMRs): bifenthrin (fat-soluble residue)



Notes:

1 STMR-P

Carbaryl** (008)

0.003

Notes:

Previous ADI was 0.01 mg/kg bw.



Periodic review was only for toxicology

Carbofuran** (096)

0.002

Notes:

Previous ADI was 0.01 mg/kg bw.



Periodic review was only for toxicology

Chlorfenvinphos* *

0.0005

VB 0400

Broccoli

W

0.05


(014)


VB 0402

Brussels sprouts

W

0.05




VB 0041

Cabbages, head

W

0.05




VR 0577

Carrot

W

0.4




VB 0404

Cauliflower

W

0.1




VS 0624

Celery

W

0.4




FC 0001

Citrus fruits

W

1




SO 0691

Cotton seed

W

0.05




VO 0440

Egg plant

W

0.05




VR 0583

Horseradish

W

0.1




VA 0384

Leek

W

0.05




GC 0645

Maize

W

0.05




MM 0095

Meat (from mammals, other than marine mammals)

W

0.2 (fat) V




ML 0107

Milk of cattle, goats and sheep

W

0.008 F V




VO 0450

Mushrooms

W

0.05




VA 0385

Onion, bulb

W

0.05




SO 0697

Peanut

W

0.05




VR 0589

Potato

W

0.05




VR 0494

Radish

W

0.1




GC 0649

Rice

W

0.05




CM 1205

Rice, polished

W

0.05




VR 0497

Swede

W

0.05




VR 0508

Sweet potato

W

0.05




VO 0448

Tomato

W

0.1




VR 0506

Turnip, Garden

W

0.05




GC 0654

Wheat

W

0.05




Residue

(for MRLs & STMRs): chlorfenvinphos, sum of E- and Z- isomers (fat-soluble residue).



Notes:

Periodic review was only for residues



Notes:

ADI refers to acid equivalent.




Previous ADI was 0.3 mg/kg bw.




Periodic review was only for toxicology

2,4-D** (020)

0.01


DDT (021)

0.02 (PTDI1

MM 0095

Meat (from mammals other than marine mammals)

5 (fat) E

1 (fat) E




Residue

(for MRLs & STMRs): sum of p.p '-DDT, o,p '-DDT, p,p '-DDE, and p,p '-TDE (p.p'-DDD) (fat-soluble residue)



Notes:

1 provisional tolerable daily intake. See 1994 report, Section 2.3

Diazinon1

0.002

PO 0840

Chicken, Edible offal of

0.02*

-

0

(022)


PE 0840

Chicken eggs

0.02*

-

0



PM 0840

Chicken meat

0.02*

-

0



MM 0814

Goat meat

2 (fat) V


0.3 (fat) 0.02 (whole muscle)



MO 0098

Kidney of cattle, goats, pigs and sheep

0.03 V

-

0.01



MO 0099

Liver of cattle, goats, pigs and sheep

0.03 V

-

0.01

Pesticide (Codex ref. No.)

ADI(mg/kg bw)


Commodity

Recommended MRL or ERL(mg/kg)

STMR (mg/kg)



CCN

Name

New

Previous




MM 0097

Meat of cattle, pigs and sheep

2 (fat) V

W1

0.3 (fat) 0.02 (whole muscle)



ML 0106

Milks

0.02 F V

W1

0.02


Residue

(for MRLs & STMRs): diazinon (fat-soluble residue)


Notes:

1 Withdrawal of existing CXL proposed by 1993 JMPR.

Dimethoate** (027)

0.002

Notes:.

ADI is for the sum of dimethoate and omethoate expressed as dimethoate




Previous ADI was 0.01 mg/kg bw.




Periodic review was only for toxicology

Disulfoton(074)

0.0003

Acute RfD 0.003 mg/kg bw.

Dithiocarbamates


AM 0660

Almond hulls

201 mb2, zm

20


(105)


TN 0660

Almonds

0.1* mb, zm

0.1*




TN 0672

Pecan

0.1* T zm

-




FP 0009

Pome fruits

5 mz, mt, pb, th, zm

5




FS 0012

Stone fruits

73 T th, zm

-




FB 0275

Strawberry

5 th

-







Residue:

total dithiocarbamates, determined as CS2 evolved during acid digestion and expressed as mg CS2/kg.



Notes:

MRLs refer to total residues from the use of any or each of the groups of dithiocarbamates.




1 The estimated temporary maximum residue level for dithiocarbamates arising from the use of ziram is 10 mg/kg, but the current draft MRL of 20 mg/kg recommended by the 1993 JMPR should be maintained to accommodate uses of maneb.




2 Based on trials with mb maneb, mz mancozeb, mt metiram, pb propineb, th thiram, zm ziram.




Underlined compounds are those on which estimates of maximum residue levels are mainly based.




3 The estimated maximum residue level for dithiocarbamates arising from the use of thiram on plums and cherries is mg/kg, but a TMRL of 7 mg/kg is recommended to accommodate uses of ziram on stone fruits.

Fenarimol

0.01

AB 0226

Apple pomace, dry

5

5 T


(192)


VS 0620

Artichoke, Globe

0.1

0.1 T




FI 0327

Banana

0.2

0.2 T




MO 1280

Cattle, kidney

0.02*

0.02* T




MO 1281

Cattle, liver

0.05

0.05 T




MM 0812

Cattle meat

0.02*

0.02* T




FS 0013

Cherries

1

1 T




DF 0269

Dried grapes (= Currants, Raisins and Sultanas)

0.2

0.2 T




FB 0269

Grapes

0.3

0.3 T




DH 1100

Hops, dry

5

-




VC 0046

Melons, except Watermelon

0.05

0.05 T




FS 0247

Peach

0.5

0.5 T




TN 0672

Pecan

0.02*

0.02* T




VO 0445

Peppers, Sweet

0.5

0.5 T




FP 0009

Pome fruits

0.3

0.3 T




FB 0275

Strawberry

1

1 T



Residue (for MRLs & STMRs): fenarimol

Ferbam** (Dithioearbamates, 105)

0.003

Notes:

group ADI for ferbam and ziram. Previous ADI was 0.02 mg/kg bw, also for ferbam and ziram.

Flumethrin* (195)

0.004

MM 0812

Cattle meat

0.2 (fat)1 V

-

0.01 (fat) 0.005 (whole muscle)



ML 0812

Cattle milk

0.05 F V

-

0.01




Honey

0.005*

-

0.005


Residue

(for MRLs & STMRs): flumethrin (fat-soluble residue)


Notes:

1 maximum residue in whole meat (muscle) reflecting approved uses was 0.01 mg/kg. Recommended MRL is on carcase fat basis.

Haloxyfop

0.0003

AL 1021

Alfalfa forage (green)

W

Prov.1


(194)


FI 0327

Banana

0.05*

Prov.1

0



MO 0812

Cattle, Edible offal of

W

Prov.1




MF 0812

Cattle fat

W

Prov.1




MM 0812

Cattle meat

W

Prov.1




ML 0812

Cattle milk

W

Prov.1




FM 0812

Cattle milk fat \ - -

W

Prov.1




PO 0840

Chicken, Edible offal of

0.1

Prov.1

0.01



PE 0840

Chicken eggs

0.01*

Prov.1

0.01



PM 0840

Chicken meat

0.01*

Prov.1

0.01



FC 0001

Citrus fruits

0.05*

Prov.1

0



SO 0691

Cotton seed

0.2

Prov.1

0.09



OC 0691

Cotton seed oil, crude

0.5

Prov.1

0.1 P2



AM 1051

Fodder beet

0.3

Prov.1

0.02



AV 1051

Fodder beet leaves or tops

W

Prov.1




FB 0269

Grapes

0.05*

Prov.1

0



SO 0697

Peanut

0.05

Prov.1

0.03



VP 0063

Peas (pods and succulent = immature seeds)

0.2

-

0.02



FP 0009

Pome fruits

0.05*

Prov.1

0



VD 0070

Pulses (dry)

0.2

Prov.1

0.03



VR 0589

Potato

0.1

Prov.1

0.04



SO 0495

Rape seed

2

Prov.1

0.17




Rape seed meal



0.15 P



OC 0495

Rape seed oil, crude

5

Prov.1

0.36 P



OR 0495

Rape seed oil, edible

5

Prov.1

0.28 P



CM 1206

Rice bran, unprocessed

0.02*

Prov.1

0.02 P



CM 0649

Rice, husked

0.02*

Prov.1

0



CM 1205

Rice, polished

0.02*

Prov.1

0




Soya bean



0.03 (Pulses (dry))




Soya bean meal



0.03 P



OC 0541

Soya bean oil, crude

0.2

Prov.1

0.02 P



OR 0541

Soya bean oil, refined

0.2

Prov.1

0.02 P



VR 0596

Sugar beet

0.3

Prov.1

0.02



AV 0596

Sugar beet leaves or tops

W

Prov.1





Sugar beet pressed pulp



0.008 P




Sugar, refined



0.002 P



SO 0702

Sunflower seed

0.2

Prov.1

0.05


Residue

(for MRLs & STMRs): haloxyfop esters, haloxyfop and its conjugates expressed as haloxyfop


Notes:

1 Provisional estimates of maximum residue levels were made by the 1995 JMPR, but were not recommended for use as MRLs.



2 STMR-P

Maleic hydrazide** (102)

0.3

Notes:

Previous ADI was 5 mg/kg bw.




Periodic review was only for toxicology

Methamidophos

0.004

VB 0041

Cabbage, Head

0.5

1

0.01

(100)


VB 0404

Cauliflower

0.5

1

0.01



FS 0247

Peach

1

1

0.16




Peach, washed fruit



0.10




Peach, juice (100% basis)



0.11 P2




Peach, jam



0.10 P




Peach, canned fruit



0.08 P



VO 0448

Tomato

1

-1

0.12


Residue

(for MRLs & STMRs): methamidophos


Notes:

1Withdrawn by 1994 JMPR



2 STMR-P



Recommended MRLs are based on residues from the use of methamidophos or acephate

Mevinphos** (053)

0.0008

Notes:

Acute RfD 0.003 mg/kg bw.




Previous ADI was 0.0015 mg/kg bw.




Periodic review was only for toxicology

Phorate (112)

0.0005

Notes:

Previous ADI confirmed

Propoxur

0.02

VL 0482

Lettuce, Head

0.5

3


(075)


VR 0589

Potato

0.02*

0.1*



Residue

(for MRLs): propoxur

Tebufenozide*

0.02

FB 0269

Grapes

0.5

-

0.12

(196)


FP 0009

Pome fruits

1

-

0.16



CM 0649

Rice, husked

0.1

-

0.03



TN 0678

Walnut

0.05

-

0.003




Apple pomace, wet



0.4 P'




Apple juice



0.02 P




Apple purée



0.04 P




Grape pomace, wet



0.36 P




Wine



0.03 P


Residue

(for MRLs & STMRs): tebufenozide (fat-soluble residue)


Notes:

1 STMR-P

Teflubenzuron*

0.01

VB 0402

Brussels sprouts

0.5

-

0.21

(190)


VB 0041

Cabbages, Head

0.2

-

0.05



FS 0014

Plums (including Prunes)

0.1

-

0.04



FP 0009

Pome fruits

1

-

0.48



VR 0589

Potato

0.05*

-

0


Residue

(for MRLs & STMRs): teflubenzuron (fat-soluble residue)


Notes:

First evaluation of residue and analytical aspects. Toxicology was evaluated in 1994.

Thiram**

0.01


Apple juice



0.55 P1

(Dithiocarbamates, 105)



Apple pomace, wet



1.9 P




Apple pomace, dry



6.93 P



FS 0013

Cherries

1

-

0.72



FS 0014

Plums (including Prunes)

1

-

0.72



FP 0009

Pome fruits

5

5

1.9



FB 0275

Strawberry

5

-

2.1


Residue

for MRLs: see dithiocarbamates



for STMRs: thiram


Notes:

1 STMR-P



Periodic review was only for residues.

Ziram**

0.003

AM 0660

Almond hulls

10 T

20

10.6

(Dithiocarbamates,


TN 0660

Almonds

0.1* T

0.1*

0.04

105)



Apple juice



0.204 P




Apple pomace, wet



2.81 P




Apple pomace, dry



3.82 P



TN 0672

Pecan

0.1* T

-

0.04



FP 0009

Pome fruits

5 T

5

2.1



FS 0012

Stone fruits

7 T

-

2.2



Residue

for MRLs: see dithiocarbamates




for STMRs: ziram



Notes:

group ADI for ferbam and ziram.




Previous ADI was 0.02 mg/kg bw, also for ferbam and ziram.


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