There are a plethora of strategies for addressing climate change which indigenous and local peoples (IPLCs) have adopted across the globe for diverse ecosystems. These strategies are however driven directly by factors relating to land or sea uses, the extent of the degradation and the dependency of IPLCs on the natural resource base for their livelihoods. To a significant extent, the response and actions to climate change by IPLCs are indirectly driven by the prevailing governance systems, economic trends and demographic changes. Overall, IPLCs response to climate change is not isolated in a vacuum but inherently interlinked to their responses to other stimuli associated with their quest to access food, water, health and energy from their surrounding natural resource base. The drivers of these interlink must be clearly reviewed, examined and documented for comprehensive policy actions.